Management of Inherited CNS Small Vessel Diseases: The CADASIL Example
Published: agosto 21, 2023
- Lacunar infarcts and vascular dementia are phenotypic characteristics of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).
- CADASIL is caused by a mutation in the NOTCH3 gene expressed in endothelial smooth muscle cells.
- This is the first paper from the American Heart Association published on the subject of inherited cerebrovascular small vessel diseases.